The IgA (Immunoglobulin A) test is a diagnostic tool used to assess the levels of IgA antibodies in the blood. IgA is the primary antibody in the body's mucous membranes and plays a crucial role in defending against infections in the respiratory and gastrointestinal tracts. This test helps in the identification and monitoring of certain autoimmune diseases, allergies, and immunodeficiencies affecting the IgA levels, providing valuable insights for diagnosis and treatment planning.
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B-lymphocytes and plasma cells synthesize a group of plasma proteins called Immunoglobulins (Ig). These molecules are classified based on the type of heavy chain into five categories: IgG, IgM, IgA, IgE, and IgD. Antibodies or Immunoglobulins identify and bind with foreign antigens like viruses, bacteria, and toxins, destroying them. Immunoglobulin A is an indicator of humoral immunity that plays a significant role in assessing local immunity, acute infectious conditions, chronic inflammation, and diseases of the liver and kidneys. Immunoglobulin A is a protein that provides local immunity and comes in serum and secretory. The secretory part can be discovered in various bodily fluids such as milk, respiratory and intestinal tract secretions, lacrimal fluid, and saliva. It works with other immune factors to defend mucous membranes against bacterial and viral infections. Serum IgA's primary function is to counteract viruses, and it plays a vital role in safeguarding the respiratory, urogenital, and gastrointestinal tracts from infection.
With the help of immunoglobulins A, doctors assess the course of diseases that occur with the activation of immunity: acute and chronic infections of bacterial and viral origin; bronchial asthma; oncological diseases of the lymphatic system (leukemia, multiple myeloma); connective tissue diseases (systemic lupus erythematosus, rheumatoid arthritis). Immunoglobulin IgA is determined in the presence of the following diseases: recurrent bacterial respiratory infections (sinusitis, pneumonia), as well as otitis and meningitis, bronchial asthma; chronic diarrhea, malabsorption syndrome; anaphylactic post-transfusion reactions; Louis Bar syndrome (ataxia - telangiectasia); Tumor diseases of the lymphoid system (myeloma, leukemia, reticulosarcoma, lymphoma). Chronic hepatitis, cirrhosis of the liver. Using the study of IgA immunoglobulin, doctors check the functioning of the liver, stomach, intestines, and lymphatic system.
The patient is advised to refrain from eating for 12-14 hours before the study. He can drink pure non-carbonated water. Doctors stop medications that may affect the results of the study. Three days before blood sampling, the patient must stop drinking alcohol.
An IgA blood test is performed to assess the levels of immunoglobulin A (IgA) in your blood. IgA is an antibody that is crucial to your immune system's defence against infections. By measuring IgA levels, this test helps evaluate the function of your immune system and provides insights into your overall health. Abnormal IgA levels can indicate immune deficiencies or autoimmune diseases. It can also help diagnose conditions like celiac disease, where IgA antibodies may be elevated in response to gluten. Discussing your IgA test results with your healthcare provider can help identify potential health issues and guide appropriate treatment if necessary.
Before an IgA blood test, you do not need to follow specific preparation guidelines. However, it is always recommended to consult your healthcare provider about any medications or supplements as they may affect your test IgA results.
The normal range for IgA levels in the blood varies depending on the laboratory but typically falls between 70 and 400 milligrams per deciliter (mg/dL). Your healthcare provider will interpret your IgA lab test results based on age, gender, medical history, and symptoms.
Low levels of IgA in the blood may indicate an increased risk of infections or underlying immune deficiency disorders, such as common variable immunodeficiency (CVID) or selective IgA deficiency. High levels of IgA in the blood may suggest an active infection, autoimmune disorder, or chronic liver disease. You can perform the IgA test in Montreal at our nearby laboratory, ensuring fast and seamless results are delivered within 24 hours.
The frequency of immunoglobulin A blood test depends on your health needs and medical history. Your healthcare provider may recommend more frequent testing if you have an underlying health condition or immunodeficiency disorder.
Certain medications, medical conditions, or lifestyle factors may affect your IgA blood test results. Some medications, such as immunosuppressants, may lower IgA levels, while certain infections or autoimmune disorders may increase IgA levels. It is important to discuss any medications, medical conditions, or lifestyle factors that may affect your immunoglobulin A blood test results with your healthcare provider.
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